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GREEN TOUCH STRIP
FLUORESCEIN SODIUM OPHTHALMIC STRIPS (1 MG)
100 STRIP BOX
Lack of understanding
Belief that use of Fluorescein is sufficient
Making decisions based on other clinical findings or reported symptoms
Cost and time commitments
Confusion over the legal status
Lissamine green is an organic dye that is synthetically produced and its molecular weight is 576.6 Daltons. Since 1923, the Biological Stain Commission (BSC) has classified dyes with similar chemical structures according to their chromophores. Lissamine green is a diphenyl-naphthyl methane derivative of the phenylmethane dye, whereas fluorescein and rose bengal fall into the category of xanthine dyes. Despite rose bengal being a derivative of fluorescein, the clinical staining patterns of lissammine green and rose bengal are the most similar, though lissamine green does not fluoresce. Unlike rose bengal which causes ocular irritation, lissamine green is well tolerated making it the preferred choice in optometric practice.
Norm’s original research1 concluded lissamine green ‘shows a high level of affinity in staining degenerated cells, dead cells and mucous fibrils, with this staining being well defined and easily visualised with a slit lamp’. Whether mucous is stained or whether it is observed as a result of applying multiple stains, has been challenged more recently by Papas.3 More research is needed before we can fully understand what stains actually do4 and numerous researchers are now focusing on this topic.
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